If he times it right, Dante can Royal Guard the lightning and counter, or even teleport with Trickster right before impact. He’s got the reflexes and tools for it.
I tested a few custom modes with my buddies where we tried crazy power matchups like that. Used a fortnite aimbot setup once offline just to study how abilities track targets, and it really showed how precise timing and movement matter more than raw power in fights like this.